Reaction Details Report a problem with these data
Target
Melatonin receptor type 1A
Ligand
BDBM50240440
Substrate
n/a
Meas. Tech.
ChEMBL_304083 (CHEMBL838521)
Ki
105±n/a nM
Citation
 Rivara, S; Lorenzi, S; Mor, M; Plazzi, PV; Spadoni, G; Bedini, A; Tarzia, G Analysis of structure-activity relationships for MT2 selective antagonists by melatonin MT1 and MT2 receptor models. J Med Chem 48:4049-60 (2005) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A protein | Mel-1A-R | Melatonin receptor type 1A | Mel1a melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin 1A | MTR1A_HUMAN | MTNR1A | Melatonin receptor
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Human
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50240440
Synonyms:
CHEMBL285718 | 4-P-PDOT | N-(4-Phenyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propionamide | N-(4-phenyl-1,2,3,4-tetrahydronaphthalen-2-yl)propionamide
Type:
Small organic molecule
Emp. Form.:
C19H21NO
Mol. Mass.:
279.16
SMILES:
CCC(=O)NC1CC(c2ccccc2)c2ccccc2C1
Structure:
Search PDB for entries with ligand similarity: