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Target
Protein RecA
Ligand
BDBM50475223
Substrate
n/a
Meas. Tech.
ChEMBL_303910 (CHEMBL828335)
Ki
46000±n/a nM
Citation
 Lee, AM; Ross, CT; Zeng, BB; Singleton, SF A molecular target for suppression of the evolution of antibiotic resistance: inhibition of the Escherichia coli RecA protein by N(6)-(1-naphthyl)-ADP. J Med Chem 48:5408-11 (2005) [PubMed]  Article 
Target
Name:
Protein RecA
Synonyms:
RECA_ECOLI | lexB | recA | recH | rnmB | tif | umuB | zab
Type:
Protein
Mol. Mass.:
37964.88
Organism:
Escherichia coli
Description:
C6EJT2
Residue:
353
Sequence:
MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTGSLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDPIYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEIGDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKFYASVRLDIRRIGAVKEGENVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELVDLGVKEKLIEKAGAWYSYKGEKIGQGKANATAWLKDNPETAKEIEKKVRELLLSNPNSTPDFSVDDSEGVAETNEDF
  
Inhibitor
Name:
BDBM50475223
Synonyms:
CHEMBL1161750
Type:
Small organic molecule
Emp. Form.:
C20H21N5O10P2
Mol. Mass.:
553.3558
SMILES:
O[C@@H]1[C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cnc2c(Nc3cccc4ccccc34)ncnc12 |r|
Structure:
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