Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50475252
Substrate
n/a
Meas. Tech.
ChEMBL_306961 (CHEMBL826905)
KOFF
0.001 s-1
Citation
 Göblyös, A; de Vries, H; Brussee, J; Ijzerman, AP Synthesis and biological evaluation of a new series of 2,3,5-substituted [1,2,4]-thiadiazoles as modulators of adenosine A1 receptors and their molecular mechanism of action. J Med Chem 48:1145-51 (2005) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
A1 adenosine receptor (hA1) | A1AR | ADENOSINE A1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT) | AA1R_HUMAN | ADORA1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36520.92
Organism:
Human
Description:
P30542
Residue:
326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVTPRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPIDEDLPEERPDD
  
Inhibitor
Name:
BDBM50475252
Synonyms:
CHEMBL541889
Type:
Small organic molecule
Emp. Form.:
C19H20BrN3S
Mol. Mass.:
402.36
SMILES:
C1CCC(C1)\N=c1\nc(-c2ccccc2)n(s1)-c1ccccc1
Structure:
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