Reaction Details Report a problem with these data
Target
Reverse transcriptase protein
Ligand
BDBM50478973
Substrate
n/a
Meas. Tech.
ChEMBL_490001 (CHEMBL984664)
Ki
110±n/a nM
Citation
 Marchand, B; White, KL; Ly, JK; Margot, NA; Wang, R; McDermott, M; Miller, MD; Götte, M Effects of the translocation status of human immunodeficiency virus type 1 reverse transcriptase on the efficiency of excision of tenofovir. Antimicrob Agents Chemother 51:2911-9 (2007) [PubMed]  Article 
Target
Name:
Reverse transcriptase protein
Synonyms:
Reverse Transcriptase | Reverse Transcriptase (A62V) | Reverse Transcriptase (F61A)
Type:
Protein
Mol. Mass.:
30203.56
Organism:
Human immunodeficiency virus 1
Description:
Q9WJQ2
Residue:
259
Sequence:
PISPIEPVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPVFAIKKKDSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGFTTPDKKHQKEPPFLWMGYEHHPDKWTVQPIVLPEKDSWTVNDIQK
  
Inhibitor
Name:
BDBM50478973
Synonyms:
CHEMBL1162283
Type:
Small organic molecule
Emp. Form.:
C9H15N5O7P2
Mol. Mass.:
367.1922
SMILES:
C[C@H](Cn1cnc2c(N)ncnc12)OCP(O)(=O)OP(O)(O)=O |r|
Structure:
Search PDB for entries with ligand similarity: