Target
Protease
Ligand
BDBM50483334
Substrate
n/a
Meas. Tech.
ChEMBL_715372 (CHEMBL1664701)
Ki
0.010000±n/a nM
Citation
 Ghosh, AKChapsal, BDBaldridge, ASteffey, MPWalters, DEKoh, YAmano, MMitsuya, H Design and synthesis of potent HIV-1 protease inhibitors incorporating hexahydrofuropyranol-derived high affinity P(2) ligands: structure-activity studies and biological evaluation. J Med Chem 54:622-34 (2011) [PubMed]  Article 
Target
Name:
Protease
Synonyms:
n/a
Type:
Enzyme
Mol. Mass.:
10904.79
Organism:
Human immunodeficiency virus 1 (HIV-1)
Description:
Q9YQ12
Residue:
99
Sequence:
PQITLWQRPFVTIKIEGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFIKVRQYDQIVIEICGKKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM50483334
Synonyms:
CHEMBL1651160
Type:
Small organic molecule
Emp. Form.:
C28H39N3O7S
Mol. Mass.:
561.69
SMILES:
[H][C@@]12CCO[C@]1([H])OCC[C@@H]2OC(=O)N[C@@H](Cc1ccccc1)[C@H](O)CN(CC(C)C)S(=O)(=O)c1ccc(N)cc1 |r|
Structure:
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