Reaction Details Report a problem with these data
Target
Solute carrier family 22 member 4
Ligand
BDBM50485565
Substrate
n/a
Meas. Tech.
ChEMBL_835945 (CHEMBL2077083)
IC50
200000±n/a nM
Citation
 Wu, X; George, RL; Huang, W; Wang, H; Conway, SJ; Leibach, FH; Ganapathy, V Structural and functional characteristics and tissue distribution pattern of rat OCTN1, an organic cation transporter, cloned from placenta. Biochim Biophys Acta 1466:315-27 (2000) [PubMed]  Article 
Target
Name:
Solute carrier family 22 member 4
Synonyms:
Organic cation/carnitine transporter 1 | Solute carrier family 22 member 4 | S22A4_RAT | Slc22a4 | Octn1
Type:
PROTEIN
Mol. Mass.:
62362.68
Organism:
Rat
Description:
ChEMBL_104608
Residue:
553
Sequence:
MRDYDEVIAFLGDWGPFQRLIFFLLSASIIPNGFNGMSVVFLAGTPEHRCLVPHTVNLSSAWRNHSIPLETKDGRQVPQSCRRYRLATIANFSALGLEPGLDVDLEQLEQESCLDGWEYSKDVFLSTIVTEWNLVCEDDWKTPLTTSLFFVGVLCGSFVSGQLSDRFGRKKVLFATMAVQTGFSFVQIFSTNWEMFTVLFAIVGMGQISNYVVAFILGTEILSKSVRILFSTLGVCTFFAIGYMVLPLFAYFIRDWRMLLLALTLPGLFCVPLWWFIPESPRWLISQRRFEEAEQIIQKAAKMNGIMAPAVIFDPLELQELNSLKQQKVFILDLFKTRNIATITVMSVMLWMLTSVGYFALSLNVPNLHGDVYLNCFLSGLIEVPAYFTAWLLLRTLPRRYIIAGVLFWGGGVLLLVQVVPEDYNFVSIGLVMLGKFGVTSAFSMLYVFTAELYPTLVRNMAVGITSMASRVGSIIAPYFVYLGAYNRLLPYILMGSLTVLIGIITLFFPESFGVTLPENLEQMQKVRGFRCGKKSTVSMDREENPKVLITAF
  
Inhibitor
Name:
BDBM50485565
Synonyms:
CHEMBL465179
Type:
Small organic molecule
Emp. Form.:
C8H12ClN7O
Mol. Mass.:
257.68
SMILES:
CN(C)c1nc(N)c(nc1Cl)C(=O)NC(N)=N
Structure:
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