Reaction Details Report a problem with these data
Target
Solute carrier organic anion transporter family member 1C1
Ligand
BDBM50344959
Substrate
n/a
Meas. Tech.
ChEMBL_838508 (CHEMBL2078136)
Ki
>100000±n/a nM
Citation
 Tohyama, K; Kusuhara, H; Sugiyama, Y Involvement of multispecific organic anion transporter, Oatp14 (Slc21a14), in the transport of thyroxine across the blood-brain barrier. Endocrinology 145:4384-91 (2004) [PubMed]  Article 
Target
Name:
Solute carrier organic anion transporter family member 1C1
Synonyms:
OATP-14 | OATP-F | OATP2 | Organic anion transporter 2 | Organic anion transporter F | Organic anion-transporting polypeptide 14 | Solute carrier family 21 member 14 | Solute carrier organic anion transporter family member 1C1 | Thyroxine transporter | SO1C1_MOUSE | Slco1c1 | Oatp1c1 | Oatpf | Slc21a14
Type:
PROTEIN
Mol. Mass.:
78347.58
Organism:
Mouse
Description:
ChEMBL_104629
Residue:
715
Sequence:
MDTSSKENAHLFHKNSAQPAGGPSFTVGYPSTEEARPCCGKLKVFLGALSFVYFAKALAEGYLKSTVTQIERRFEIPSSLVGIIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCLVMGFGTMLIAVPQFFMEKYSYEKYERYSPSSNVTPSISPCYLESSSPSPSSILGKSQNKISHECVGDSSSSMWVYVFLGNLLRGLGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGFLSLLAAVPFWCLPKTLPRSQSRENSGSTSEKSKFIDDPIHYQMAPGDDKMKIMEMAKDFLPSLKTLFRNPVYILYLCASTVQFNSLFGMVTYKPKYIEQQYGQSSSKANFVIGLINIPAVALGIFSGGIVMKKFRLGICEATKLYLGSSVFGYLLFLSLFALGCENSSVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSDSKWEPMCGDNGITYVSACLAGCQSSSRSGKNIIFSNCTCVGFAAPKSGNWSGMMGRCQKDNGCSQMFLYFLVISVITSYTLSLGGIPGYILLLRCIQPQLKSFALGIYTLAVRVLAGIPAPVYFGVLIDTSCLKWGFKKCGSRGSCRLYDSHAFRHIYLGLTTLLGTVSVFLSMAVLFVLKKKYVSKHSSLITTREKIGMSSSIKKETCAARDRGLQPKYWPGKETRL
  
Inhibitor
Name:
BDBM50344959
Synonyms:
17beta-Estradiol-17-(beta-D-glucuronide) | estradiol 17b glucuronide | CHEMBL1697724 | E17β-glucuronide
Type:
Small organic molecule
Emp. Form.:
C24H32O8
Mol. Mass.:
n/a
SMILES:
C[C@]12CC[C@@H]3c4ccc(cc4CC[C@H]3[C@@H]1CC[C@@H]2O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)C(=O)O)O)O)O)O
Structure:
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