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Target
Solute carrier organic anion transporter family member 1C1
Ligand
BDBM18862
Substrate
n/a
Meas. Tech.
ChEMBL_838508 (CHEMBL2078136)
Ki
2150±n/a nM
Citation
 Tohyama, K; Kusuhara, H; Sugiyama, Y Involvement of multispecific organic anion transporter, Oatp14 (Slc21a14), in the transport of thyroxine across the blood-brain barrier. Endocrinology 145:4384-91 (2004) [PubMed]  Article 
Target
Name:
Solute carrier organic anion transporter family member 1C1
Synonyms:
OATP-14 | OATP-F | OATP2 | Organic anion transporter 2 | Organic anion transporter F | Organic anion-transporting polypeptide 14 | Solute carrier family 21 member 14 | Solute carrier organic anion transporter family member 1C1 | Thyroxine transporter | SO1C1_MOUSE | Slco1c1 | Oatp1c1 | Oatpf | Slc21a14
Type:
PROTEIN
Mol. Mass.:
78347.58
Organism:
Mouse
Description:
ChEMBL_104629
Residue:
715
Sequence:
MDTSSKENAHLFHKNSAQPAGGPSFTVGYPSTEEARPCCGKLKVFLGALSFVYFAKALAEGYLKSTVTQIERRFEIPSSLVGIIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCLVMGFGTMLIAVPQFFMEKYSYEKYERYSPSSNVTPSISPCYLESSSPSPSSILGKSQNKISHECVGDSSSSMWVYVFLGNLLRGLGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGFLSLLAAVPFWCLPKTLPRSQSRENSGSTSEKSKFIDDPIHYQMAPGDDKMKIMEMAKDFLPSLKTLFRNPVYILYLCASTVQFNSLFGMVTYKPKYIEQQYGQSSSKANFVIGLINIPAVALGIFSGGIVMKKFRLGICEATKLYLGSSVFGYLLFLSLFALGCENSSVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSDSKWEPMCGDNGITYVSACLAGCQSSSRSGKNIIFSNCTCVGFAAPKSGNWSGMMGRCQKDNGCSQMFLYFLVISVITSYTLSLGGIPGYILLLRCIQPQLKSFALGIYTLAVRVLAGIPAPVYFGVLIDTSCLKWGFKKCGSRGSCRLYDSHAFRHIYLGLTTLLGTVSVFLSMAVLFVLKKKYVSKHSSLITTREKIGMSSSIKKETCAARDRGLQPKYWPGKETRL
  
Inhibitor
Name:
BDBM18862
Synonyms:
2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetic acid | CHEMBL41632 | Tiratricol | TRIAC | Triiodothyroacetic acid, 3 | US10322118, Entry Tiratricol
Type:
Small organic molecule
Emp. Form.:
C14H9I3O4
Mol. Mass.:
621.76
SMILES:
c1cc(c(cc1Oc2c(cc(cc2I)CC(=O)O)I)I)O
Structure:
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