Reaction Details Report a problem with these data
Target
Solute carrier organic anion transporter family member 1C1
Ligand
BDBM50206509
Substrate
n/a
Meas. Tech.
ChEMBL_838508 (CHEMBL2078136)
Ki
293000±n/a nM
Citation
 Tohyama, K; Kusuhara, H; Sugiyama, Y Involvement of multispecific organic anion transporter, Oatp14 (Slc21a14), in the transport of thyroxine across the blood-brain barrier. Endocrinology 145:4384-91 (2004) [PubMed]  Article 
Target
Name:
Solute carrier organic anion transporter family member 1C1
Synonyms:
OATP-14 | OATP-F | OATP2 | Organic anion transporter 2 | Organic anion transporter F | Organic anion-transporting polypeptide 14 | Solute carrier family 21 member 14 | Solute carrier organic anion transporter family member 1C1 | Thyroxine transporter | SO1C1_MOUSE | Slco1c1 | Oatp1c1 | Oatpf | Slc21a14
Type:
PROTEIN
Mol. Mass.:
78347.58
Organism:
Mouse
Description:
ChEMBL_104629
Residue:
715
Sequence:
MDTSSKENAHLFHKNSAQPAGGPSFTVGYPSTEEARPCCGKLKVFLGALSFVYFAKALAEGYLKSTVTQIERRFEIPSSLVGIIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCLVMGFGTMLIAVPQFFMEKYSYEKYERYSPSSNVTPSISPCYLESSSPSPSSILGKSQNKISHECVGDSSSSMWVYVFLGNLLRGLGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPIFGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGFLSLLAAVPFWCLPKTLPRSQSRENSGSTSEKSKFIDDPIHYQMAPGDDKMKIMEMAKDFLPSLKTLFRNPVYILYLCASTVQFNSLFGMVTYKPKYIEQQYGQSSSKANFVIGLINIPAVALGIFSGGIVMKKFRLGICEATKLYLGSSVFGYLLFLSLFALGCENSSVAGLTVSYQGTKPVSYHERALFSDCNSRCKCSDSKWEPMCGDNGITYVSACLAGCQSSSRSGKNIIFSNCTCVGFAAPKSGNWSGMMGRCQKDNGCSQMFLYFLVISVITSYTLSLGGIPGYILLLRCIQPQLKSFALGIYTLAVRVLAGIPAPVYFGVLIDTSCLKWGFKKCGSRGSCRLYDSHAFRHIYLGLTTLLGTVSVFLSMAVLFVLKKKYVSKHSSLITTREKIGMSSSIKKETCAARDRGLQPKYWPGKETRL
  
Inhibitor
Name:
BDBM50206509
Synonyms:
CHEMBL897 | 4-Dipropylsulfamoyl-benzoic acid(probenecid) | 4-Dipropylsulfamoyl-benzoic acid | Benemid | Probalan | 4-Dipropylsulfamoyl-benzoic acid anion | PROBENECID | US20240116873, Compound Probenecid
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
CCCN(CCC)S(=O)(=O)c1ccc(cc1)C(=O)O
Structure:
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