Reaction Details Report a problem with these data
Target
Acetolactate synthase, chloroplastic
Ligand
BDBM50424586
Substrate
n/a
Meas. Tech.
ChEMBL_908493
Ki
253±n/a nM
Citation
 McCourt, JA; Pang, SS; King-Scott, J; Guddat, LW; Duggleby, RG Herbicide-binding sites revealed in the structure of plant acetohydroxyacid synthase. Proc Natl Acad Sci U S A 103:569-73 (2006) [PubMed]  Article
Target
Name:
Acetolactate synthase, chloroplastic
Synonyms:
Acetolactate synthase
Type:
PROTEIN
Mol. Mass.:
72585.19
Organism:
Arabidopsis thaliana
Description:
ChEMBL_934103
Residue:
670
Sequence:
MAAATTTTTTSSSISFSTKPSPSSSKSPLPISRFSLPFSLNPNKSSSSSRRRGIKSSSPSSISAVLNTTTNVTTTPSPTKPTKPETFISRFAPDQPRKGADILVEALERQGVETVFAYPGGASMEIHQALTRSSSIRNVLPRHEQGGVFAAEGYARSSGKPGICIATSGPGATNLVSGLADALLDSVPLVAITGQVPRRMIGTDAFQETPIVEVTRSITKHNYLVMDVEDIPRIIEEAFFLATSGRPGPVLVDVPKDIQQQLAIPNWEQAMRLPGYMSRMPKPPEDSHLEQIVRLISESKKPVLYVGGGCLNSSDELGRFVELTGIPVASTLMGLGSYPCDDELSLHMLGMHGTVYANYAVEHSDLLLAFGVRFDDRVTGKLEAFASRAKIVHIDIDSAEIGKNKTPHVSVCGDVKLALQGMNKVLENRAEELKLDFGVWRNELNVQKQKFPLSFKTFGEAIPPQYAIKVLDELTDGKAIISTGVGQHQMWAAQFYNYKKPRQWLSSGGLGAMGFGLPAAIGASVANPDAIVVDIDGDGSFIMNVQELATIRVENLPVKVLLLNNQHLGMVMQWEDRFYKANRAHTFLGDPAQEDEIFPNMLLFAAACGIPAARVTKKADLREAIQTMLDTPGPYLLDVICPHQEHVLPMIPSGGTFNDVITEGDGRIKY
  
Inhibitor
Name:
BDBM50424586
Synonyms:
CHEMBL1229780 | Tribenuron Methyl
Type:
Small organic molecule
Emp. Form.:
C15H17N5O6S
Mol. Mass.:
395.39
SMILES:
COC(=O)c1ccccc1S(=O)(=O)NC(=O)N(C)c1nc(C)nc(OC)n1
Structure:
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