Reaction Details Report a problem with these data
Target
D(2) dopamine receptor
Ligand
BDBM50020680
Substrate
n/a
Meas. Tech.
ChEMBL_910805 (CHEMBL3057561)
EC50
76±n/a nM
Citation
  TBA Med Chem Res 13:25-33 (2004)    Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50020680
Synonyms:
4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one | CHEMBL589 | ROPINIROLE
Type:
Small organic molecule
Emp. Form.:
C16H24N2O
Mol. Mass.:
260.3746
SMILES:
CCCN(CCC)CCc1cccc2NC(=O)Cc12
Structure:
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