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Target
Type-1 angiotensin II receptor
Ligand
BDBM50044499
Substrate
n/a
Meas. Tech.
ChEMBL_911177 (CHEMBL3055839)
IC50
12±n/a nM
Citation
  TBA Med Chem Res 19:375-391 (2010)    Article 
Target
Name:
Type-1 angiotensin II receptor
Synonyms:
AGTR1 | AGTR1_RABIT | ANGIOTENSIN AT1 | Angiotensin II receptor | Angiotensin II type 1a (AT-1a) receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
41009.15
Organism:
RABBIT
Description:
ANGIOTENSIN AT1 AGTR1 RABBIT::P34976
Residue:
359
Sequence:
MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE
  
Inhibitor
Name:
BDBM50044499
Synonyms:
5-Butyl-2-(3-methyl-benzyl)-4-[2'-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-2,4-dihydro-[1,2,4]triazol-3-one | CHEMBL87129
Type:
Small organic molecule
Emp. Form.:
C28H29N7O
Mol. Mass.:
479.5762
SMILES:
CCCCc1nn(Cc2cccc(C)c2)c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
Structure:
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