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Target
Nicotinic acetylcholine receptor alpha 5 subunit
Ligand
BDBM50143314
Substrate
n/a
Meas. Tech.
ChEMBL_916315 (CHEMBL3081642)
IC50
1340±n/a nM
Citation
 Kagabu, S; Kiriyama, K; Nishiwaki, H; Kumamoto, Y; Tada, T; Nishimura, K Asymmetric chloronicotinyl insecticide, 1-[1-(6-chloro-3-pyridyl)ethyl]-2-nitroiminoimidazolidine: preparation, resolution and biological activities toward insects and their nerve preparations. Biosci Biotechnol Biochem 67:980-8 (2003) [PubMed]  Article 
Target
Name:
Nicotinic acetylcholine receptor alpha 5 subunit
Synonyms:
Nicotinic acetylcholine receptor alpha 5 subunit | nAChRalpha5
Type:
PROTEIN
Mol. Mass.:
88489.00
Organism:
House fly
Description:
ChEMBL_106552
Residue:
781
Sequence:
MMWEMLILWAVHLSLTAIATLYANVRTALSQTAQQIVRAVIAATTLPIIQRIQQQQHETEKQQQQLQHGKHVEDIHLPAAGARYASASSSRLPPSSADATIWPRAPPELPQTEKLSSAPPPPSSSSTLLMQTKPAHKKPVHGRNFPPQQKNRMQPVSHLQYQQQQQQQLSLPSPAEPQPQHYKQQQQQQGQERLGQQVNINNITSSSNGGNTCSSNSFTATTSIAATTTTSILTLWQHCHRRYRPHQLLPLLTTKGLNKYSWIFLLIYLNLSAKVCLAGYNEKRLLHDLLDTYNTLERPVLNESDPLQLSFGLTLMQIIDVDEKNQLLVTNVWLKLEWNDMNLRWNTSDYGGIKDLRIPPHRIWKPDVLMYNSADEGFDGTYQTNVVVRNNGSCLYVPPGIFKSTCKIDITWFPFDDQRCEMKFGSWTYDGFQLDLQLQDETGGDISSYVLNGEWELLGVPGKRNEIYYNCCPEPYIDITFAIIIRRRTLYYFFNLIIPCVLIASMALLGFTLPPDSGEKLSLGVTILLSLTVFLNMVAETMPATSDAVPLLGTYFNCIMFMVASSVVSTILILNYHHRNADTHEMSEWIRVVFLCWLPWILRMHRPGRPIIMDFTSTPCSDTSSERKHQILSDVELKERSSKSLLANVLDIDDDFRNVRPMTPGGTLPHNPAFYRTVYGYLENLQGDDGSIGPIGSTRMPDAVTHHTCIKTQTEYELSLILKEIRFITDQLRKEDEENGIANDWKFAAMVVDRLCLIIFTMFAILATIAVLLSAPHVIVS
  
Inhibitor
Name:
BDBM50143314
Synonyms:
CHEMBL298826 | (+)-Epibatidine | 2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane (epibatidine) | EPIBATIDINE | (1R,2R,4S)-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]heptane | (-)-epibatidine
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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