Reaction Details
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Histamine H3 receptor
Ligand
BDBM50458224
Substrate
n/a
Meas. Tech.
ChEMBL_931021 (CHEMBL3070469)
Ki
4.0±n/a nM
Citation
Guryn, R; Staszewski, M; Walczy?ski, K Non-imidazole histamine H Med Chem Res 22:3640-3652 (2013) [PubMed] Article More Info.:
Target
Name:
Histamine H3 receptor
Synonyms:
HH3R | HRH3_RAT | Hrh3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
48607.98
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
445
Sequence:
MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK
Inhibitor
Name:
BDBM50458224
Synonyms:
CHEMBL2297871
Type:
Small organic molecule
Emp. Form.:
C18H25NO2
Mol. Mass.:
287.3966
SMILES:
O=C(C1CC1)c1ccc(OCCCN2CCCCC2)cc1
Structure:
