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Target
Kappa-type opioid receptor
Ligand
BDBM50493711
Substrate
n/a
Meas. Tech.
ChEMBL_988382 (CHEMBL2437809)
Ki
4.8±n/a nM
Citation
 Loriga, G; Lazzari, P; Ruiu, S; Marchese, G; Manca, I; Casu, GL; Dessė, C; Pinna, GA; Asproni, B; Murineddu, G Synthesis and biological evaluation of novel delta (?) opioid receptor ligands with diazatricyclodecane skeletons. Eur J Med Chem 69:413-26 (2013) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
KOR-1 | MSL-1 | OPIATE Kappa | OPRK_MOUSE | Oprk1
Type:
Enzyme
Mol. Mass.:
42656.78
Organism:
Mus musculus (Mouse)
Description:
P33534
Residue:
380
Sequence:
MESPIQIFRGDPGPTCSPSACLLPNSSSWFPNWAESDSNGSVGSEDQQLESAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSAVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLASSVGISAIVLGGTKVREDVDVIECSLQFPDDEYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPVLYAFLDENFKRCFRDFCFPIKMRMERQSTNRVRNTVQDPASMRDVGGMNKPV
  
Inhibitor
Name:
BDBM50493711
Synonyms:
CHEMBL2436050
Type:
Small organic molecule
Emp. Form.:
C29H37N3O2
Mol. Mass.:
459.623
SMILES:
CCN(CC)C(=O)c1ccc(cc1)C(N1C2CCC1C1CCC2N1CC=C)c1cccc(O)c1 |TLB:21:22:14:17.16,20:19:14:17.16,13:14:23:21.20,THB:17:18:23:21.20,16:15:23:21.20,24:23:14:17.16|
Structure:
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