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Target
Trace amine-associated receptor 1
Ligand
BDBM50359500
Substrate
n/a
Meas. Tech.
ChEMBL_1287610 (CHEMBL3110492)
EC50
1109±n/a nM
Citation
 Reese, EA; Norimatsu, Y; Grandy, MS; Suchland, KL; Bunzow, JR; Grandy, DK Exploring the determinants of trace amine-associated receptor 1's functional selectivity for the stereoisomers of amphetamine and methamphetamine. J Med Chem 57:378-90 (2014) [PubMed]  Article 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
Trace amine receptor 1 (TARR1) | Trace amine-associated receptor1 | TAAR1_RAT | Taar1 | Ta1 | Tar1 | Trar1 | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor 1
Type:
Enzyme
Mol. Mass.:
38034.73
Organism:
Rat
Description:
Q923Y9
Residue:
332
Sequence:
MHLCHNSANISHTNSNWSRDVRASLYSLISLIILTTLVGNLIVIISISHFKQLHTPTNWLLHSMAVVDFLLGCLVMPYSMVRTVEHCWYFGELFCKLHTSTDIMLSSASILHLAFISIDRYYAVCDPLRYKAKINLAAIFVMILISWSLPAVFAFGMIFLELNLEGVEELYHNQVFCLRGCFPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRANLQVGLEGESRAPQSKETKAAKTLGIMVGVFLLCWCPFFFCMVLDPFLGYVIPPTLNDTLNWFGYLNSAFNPMVYAFFYPWFRRALKMVLFGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM50359500
Synonyms:
CHEMBL1927030 | (R)Methamphetamine
Type:
Small organic molecule
Emp. Form.:
C10H15N
Mol. Mass.:
n/a
SMILES:
CN[C@H](C)Cc1ccccc1 |r|
Structure:
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