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Target
Trace amine-associated receptor 1
Ligand
BDBM50022723
Substrate
n/a
Meas. Tech.
ChEMBL_1287608 (CHEMBL3110490)
EC50
14±n/a nM
Citation
 Reese, EA; Norimatsu, Y; Grandy, MS; Suchland, KL; Bunzow, JR; Grandy, DK Exploring the determinants of trace amine-associated receptor 1's functional selectivity for the stereoisomers of amphetamine and methamphetamine. J Med Chem 57:378-90 (2014) [PubMed]  Article 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
Trace amine receptor 1 (TARR1) | Trace amine-associated receptor1 | TAAR1_RAT | Taar1 | Ta1 | Tar1 | Trar1 | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor 1
Type:
Enzyme
Mol. Mass.:
38034.73
Organism:
Rat
Description:
Q923Y9
Residue:
332
Sequence:
MHLCHNSANISHTNSNWSRDVRASLYSLISLIILTTLVGNLIVIISISHFKQLHTPTNWLLHSMAVVDFLLGCLVMPYSMVRTVEHCWYFGELFCKLHTSTDIMLSSASILHLAFISIDRYYAVCDPLRYKAKINLAAIFVMILISWSLPAVFAFGMIFLELNLEGVEELYHNQVFCLRGCFPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRANLQVGLEGESRAPQSKETKAAKTLGIMVGVFLLCWCPFFFCMVLDPFLGYVIPPTLNDTLNWFGYLNSAFNPMVYAFFYPWFRRALKMVLFGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM50022723
Synonyms:
(2S)-1-phenylpropan-2-amine | (S)-amphetamine | (+)-(S)-amphetamine | (+)-alpha-methylphenethylamine | (+)-alpha-methylphenylethylamine | (S)-(+)-amphetamine | (S)-(+)-beta-phenylisopropylamine | (S)-1-phenyl-2-aminopropane | (S)-1-phenyl-2-propylamine | (S)-alpha-methylbenzeneethanamine | (alphaS)-alpha-methylbenzeneethanamine | Dextroamphetamine | d-amphetamine | dexamphetamine | CHEMBL612
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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