Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM50359500
Substrate
n/a
Meas. Tech.
ChEMBL_1287611 (CHEMBL3110493)
EC50
843±n/a nM
Citation
 Reese, EA; Norimatsu, Y; Grandy, MS; Suchland, KL; Bunzow, JR; Grandy, DK Exploring the determinants of trace amine-associated receptor 1's functional selectivity for the stereoisomers of amphetamine and methamphetamine. J Med Chem 57:378-90 (2014) [PubMed]  Article 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
Trace amine receptor 1 (TARR1) | Trace amine-associated receptor1 | TAAR1_MOUSE | Taar1 | Ta1 | Tar1 | Trar1 | Trace amine-associated receptor 1 (TAAR1)
Type:
Protein
Mol. Mass.:
37635.41
Organism:
Mouse
Description:
Q923Y8
Residue:
332
Sequence:
MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM50359500
Synonyms:
CHEMBL1927030 | (R)Methamphetamine
Type:
Small organic molecule
Emp. Form.:
C10H15N
Mol. Mass.:
n/a
SMILES:
CN[C@H](C)Cc1ccccc1 |r|
Structure:
Search PDB for entries with ligand similarity: