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Target
Carbonic anhydrase 1
Ligand
BDBM50499188
Substrate
n/a
Meas. Tech.
ChEMBL_1538230 (CHEMBL3737169)
Ki
6000000±n/a nM
Citation
 Cincinelli, A; Martellini, T; Vullo, D; Supuran, CT Anion and sulfonamide inhibition studies of an ?-carbonic anhydrase from the Antarctic hemoglobinless fish Chionodraco hamatus. Bioorg Med Chem Lett 25:5485-9 (2015) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 1
Synonyms:
CA-I | CA1 | CAB | CAH1_HUMAN | Carbonate dehydratase I | Carbonic anhydrase | Carbonic anhydrase 1 (CA I) | Carbonic anhydrase 1 (CA-I) | Carbonic anhydrase 1 (Recombinant CA I) | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase B | Carbonic anhydrase I | Carbonic anhydrase I (CA I) | Carbonic anhydrase I (CA-I) | Carbonic anhydrase I (CAI) | Carbonic anhydrase I (hCA I) | Carbonic anhydrase isoenzyme I (hCA I) | hCA
Type:
Enzyme
Mol. Mass.:
28873.37
Organism:
Homo sapiens (Human)
Description:
P00915
Residue:
261
Sequence:
MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIINVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQHNNRPTQPLKGRTVRASF
  
Inhibitor
Name:
BDBM50499188
Synonyms:
CHEBI:17883 | E507 | Hydrochloric Acid
Type:
Small organic molecule
Emp. Form.:
ClH
Mol. Mass.:
36.461
SMILES:
Cl
Structure:
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