Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50499212
Substrate
n/a
Meas. Tech.
ChEMBL_1538268 (CHEMBL3737380)
Ki
24±n/a nM
Citation
 Gawaskar, S; Schepmann, D; Bonifazi, A; Robaa, D; Sippl, W; Wünsch, B Benzo[7]annulene-based GluN2B selective NMDA receptor antagonists: Surprising effect of a nitro group in 2-position. Bioorg Med Chem Lett 25:5748-51 (2015) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Sigma-1 receptor | Sigma1-receptor | Sterol isomerase-like protein | Sigma1R | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | SGMR1_CAVPO | SIGMAR1 | OPRS1
Type:
Protein
Mol. Mass.:
25307.17
Organism:
Guinea pig
Description:
Q60492
Residue:
223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSKLIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50499212
Synonyms:
CHEMBL3736502
Type:
Small organic molecule
Emp. Form.:
C21H26N2O2
Mol. Mass.:
338.45
SMILES:
[O-][N+](=O)c1ccc2CCC(CCc2c1)NCCCCc1ccccc1
Structure:
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