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Target
Vasopressin V2 receptor
Ligand
BDBM50052954
Substrate
n/a
Meas. Tech.
ChEMBL_215007 (CHEMBL818806)
IC50
18±n/a nM
Citation
 Ogawa, H; Yamashita, H; Kondo, K; Yamamura, Y; Miyamoto, H; Kan, K; Kitano, K; Tanaka, M; Nakaya, K; Nakamura, S; Mori, T; Tominaga, M; Yabuuchi, Y Orally active, nonpeptide vasopressin V2 receptor antagonists: a novel series of 1-[4-(benzoylamino)benzoyl]-2,3,4,5-tetrahydro-1H-benzazepines and related compounds. J Med Chem 39:3547-55 (1996) [PubMed]  Article 
Target
Name:
Vasopressin V2 receptor
Synonyms:
VASOPRESSIN V2 | Renal-type arginine vasopressin receptor | AVPR V2 | Antidiuretic hormone receptor | V2R_RAT | Avpr2 | Vasopressin receptor
Type:
G-protein coupled receptor
Mol. Mass.:
40761.85
Organism:
Rat
Description:
n/a
Residue:
371
Sequence:
MLLVSTVSAVPGLFSPPSSPSNSSQEELLDDRDPLLVRAELALLSTIFVAVALSNGLVLGALIRRGRRGRWAPMHVFISHLCLADLAVALFQVLPQLAWDATDRFHGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQRDVGNGSGVFDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHASLVPGPSERAGRRRRGRRTGSPSEGAHVSAAMAKTVRMTLVIVIVYVLCWAPFFLVQLWAAWDPEAPLERPPFVLLMLLASLNSCTNPWIYASFSSSVSSELRSLLCCAQRHTTHSLGPQDESCATASSSLMKDTPS
  
Inhibitor
Name:
BDBM50052954
Synonyms:
2-Methyl-N-[4-(2,3,4,5-tetrahydro-benzo[b]azepine-1-carbonyl)-phenyl]-benzamide | CHEMBL119793
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
Cc1ccccc1C(=O)Nc1ccc(cc1)C(=O)N1CCCCc2ccccc12
Structure:
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