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Target
Protein Rev
Ligand
BDBM50503727
Substrate
n/a
Meas. Tech.
ChEMBL_1811902 (CHEMBL4311362)
IC50
17000±n/a nM
Citation
 Simon, B; Walmsley, C; Jackson, VJ; Garvey, EP; Slater, MJ; Berrisford, DJ; Gardiner, JM Evaluation of neomycin analogues for HIV-1 RRE RNA recognition identifies enhanced activity simplified neamine analogues. Bioorg Med Chem Lett 29:339-341 (2019) [PubMed]  Article 
Target
Name:
Protein Rev
Synonyms:
Human immunodeficiency virus type 1 REV | REV_HV1H2 | rev
Type:
PROTEIN
Mol. Mass.:
13078.11
Organism:
Human immunodeficiency virus 1
Description:
ChEMBL_79479
Residue:
116
Sequence:
MAGRSGDSDEELIRTVRLIKLLYQSNPPPNPEGTRQARRNRRRRWRERQRQIHSISERILGTYLGRSAEPVPLQLPPLERLTLDCNEDCGTSGTQGVGSPQILVESPTVLESGTKE
  
Inhibitor
Name:
BDBM50503727
Synonyms:
CHEMBL4560686
Type:
Small organic molecule
Emp. Form.:
C27H48N4O7
Mol. Mass.:
540.6926
SMILES:
[H][C@]1(O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O)[C@H]2O)O[C@H](CNCc2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)[C@@H](O)[C@H](O)[C@H]1N |r|
Structure:
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