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Target
Carbonic anhydrase 5A, mitochondrial
Ligand
BDBM50503799
Substrate
n/a
Meas. Tech.
ChEMBL_1812149 (CHEMBL4311609)
Kd
0.110000±n/a nM
Citation
 Vaškevičienė, I; Paketurytė, V; Pajanok, N; Žukauskas, Š; Sapijanskaitė, B; Kantminienė, K; Mickevičius, V; Zubrienė, A; Matulis, D Pyrrolidinone-bearing methylated and halogenated benzenesulfonamides as inhibitors of carbonic anhydrases. Bioorg Med Chem 27:322-337 (2019) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 5A, mitochondrial
Synonyms:
CA-VA | Carbonic anhydrase 5A (CA VA) | Carbonic anhydrase 5A, mitochondrial | Carbonic anhydrase VA (CA VA) | Carbonate dehydratase VA | Carbonic anhydrase 5A, mitochondrial precursor | CAH5A_HUMAN | CA5A | CA5 | Carbonic anhydrase V | Carbonic Anhydrase VA
Type:
Enzyme
Mol. Mass.:
34755.54
Organism:
Human
Description:
Human (cloned) isozyme
Residue:
305
Sequence:
MLGRNTWKTSAFSFLVEQMWAPLWSRSMRPGRWCSQRSCAWQTSNNTLHPLWTVPVSVPGGTRQSPINIQWRDSVYDPQLKPLRVSYEAASCLYIWNTGYLFQVEFDDATEASGISGGPLENHYRLKQFHFHWGAVNEGGSEHTVDGHAYPAELHLVHWNSVKYQNYKEAVVGENGLAVIGVFLKLGAHHQTLQRLVDILPEIKHKDARAAMRPFDPSTLLPTCWDYWTYAGSLTTPPLTESVTWIIQKEPVEVAPSQLSAFRTLLFSALGEEEKMMVNNYRPLQPLMNRKVWASFQATNEGTRS
  
Inhibitor
Name:
BDBM50503799
Synonyms:
CHEMBL4474833
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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