Target
Peroxisome proliferator-activated receptor gamma
Ligand
BDBM55936
Substrate
n/a
Meas. Tech.
ChEMBL_1813295 (CHEMBL4312869)
EC50
2.0±n/a nM
Citation
 Ling, TMiller, DJLang, WHGriffith, ERodriguez-Cortes, AEl Ayachi, IPalacios, GMin, JMiranda-Carboni, GLee, RERivas, F Mechanistic Insight on the Mode of Action of Colletoic Acid. J Med Chem 62:6925-6940 (2019) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor gamma
Synonyms:
NR1C3 | Nuclear receptor subfamily 1 group C member 3 | PPAR-gamma | PPARG | PPARG_HUMAN | Peroxisome proliferator-activated receptor | Peroxisome proliferator-activated receptor gamma (PPAR gamma) | Peroxisome proliferator-activated receptor gamma (PPARG) | Peroxisome proliferator-activated receptor gamma (PPARĪ³) | Peroxisome proliferator-activated receptor gamma/Nuclear receptor corepressor 2 | peroxisome proliferator-activated receptor gamma isoform 2
Type:
Nuclear Receptor
Mol. Mass.:
57613.46
Organism:
Homo sapiens (Human)
Description:
P37231
Residue:
505
Sequence:
MGETLGDSPIDPESDSFTDTLSANISQEMTMVDTEMPFWPTNFGISSVDLSVMEDHSHSFDIKPFTTVDFSSISTPHYEDIPFTRTDPVVADYKYDLKLQEYQSAIKVEPASPPYYSEKTQLYNKPHEEPSNSLMAIECRVCGDKASGFHYGVHACEGCKGFFRRTIRLKLIYDRCDLNCRIHKKSRNKCQYCRFQKCLAVGMSHNAIRFGRMPQAEKEKLLAEISSDIDQLNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMNSLMMGEDKIKFKHITPLQEQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQVTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFMEPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLLQALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMSLHPLLQEIYKDLY
  
Inhibitor
Name:
BDBM55936
Synonyms:
2-Chloro-5-nitrobenzanilide | 2-chloranyl-5-nitro-N-phenyl-benzamide | 2-chloro-5-nitro-N-phenyl-benzamide | 2-chloro-5-nitro-N-phenylbenzamide | MLS001056751 | SMR000326735 | cid_644213
Type:
Small organic molecule
Emp. Form.:
C13H9ClN2O3
Mol. Mass.:
276.675
SMILES:
[O-][N+](=O)c1ccc(Cl)c(c1)C(=O)Nc1ccccc1
Structure:
Search PDB for entries with ligand similarity: