Reaction Details Report a problem with these data
Target
Carbonic anhydrase 3
Ligand
BDBM50504911
Substrate
n/a
Meas. Tech.
ChEMBL_1816900 (CHEMBL4316474)
Kd
50000±n/a nM
Citation
 Zakšauskas, A; Čapkauskaitė, E; Jezepčikas, L; Linkuvienė, V; Paketurytė, V; Smirnov, A; Leitans, J; Kazaks, A; Dvinskis, E; Manakova, E; Gražulis, S; Tars, K; Matulis, D Halogenated and di-substituted benzenesulfonamides as selective inhibitors of carbonic anhydrase isoforms. Eur J Med Chem 185:0 (2020) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 3
Synonyms:
Carbonic anhydrase 3 (CA III) | CA-III | Carbonate dehydratase III | Carbonic anhydrase III (CA III) | CAH3_HUMAN | CA3 | Carbonic anhydrase | Carbonic Anhydrase III
Type:
Enzyme
Mol. Mass.:
29562.11
Organism:
Human
Description:
Human cloned isozyme.
Residue:
260
Sequence:
MAKEWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTILNNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDPSCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVSNWRPPQPINNRVVRASFK
  
Inhibitor
Name:
BDBM50504911
Synonyms:
CHEMBL4456851
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: