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Target
Carbonic anhydrase 2
Ligand
BDBM50504930
Substrate
n/a
Meas. Tech.
ChEMBL_1816899 (CHEMBL4316473)
Kd
22±n/a nM
Citation
 Zakšauskas, A; Čapkauskaitė, E; Jezepčikas, L; Linkuvienė, V; Paketurytė, V; Smirnov, A; Leitans, J; Kazaks, A; Dvinskis, E; Manakova, E; Gražulis, S; Tars, K; Matulis, D Halogenated and di-substituted benzenesulfonamides as selective inhibitors of carbonic anhydrase isoforms. Eur J Med Chem 185:0 (2020) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 2
Synonyms:
CAH2_HUMAN | CA2 | CA-II | CAC | Carbonate dehydratase II | Carbonic anhydrase 2 (CA II) | Carbonic anhydrase 2 (CA-II) | Carbonic anhydrase 2 (Recombinant CA II) | Carbonic anhydrase C | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II) | Carbonic anhydrase II (CAII) | Carbonic anhydrase II (hCA II) | Carbonic anhydrase isoenzyme II (hCA II)
Type:
Enzyme
Mol. Mass.:
29250.71
Organism:
Human
Description:
P00918
Residue:
260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKPLSVSYDQATSLRILNNGHAFNVEFDDSQDKAVLKGGPLDGTYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHLVHWNTKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFDPRGLLPESLDYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEPEELMVDNWRPAQPLKNRQIKASFK
  
Inhibitor
Name:
BDBM50504930
Synonyms:
CHEMBL4515586
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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