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Target
Potassium channel subfamily K member 9
Ligand
BDBM50350790
Substrate
n/a
Meas. Tech.
ChEMBL_1822418 (CHEMBL4322182)
IC50
100000±n/a nM
Citation
 Bedoya, M; Rinné, S; Kiper, AK; Decher, N; González, W; Ramírez, D TASK Channels Pharmacology: New Challenges in Drug Design. J Med Chem 62:10044-10058 (2019) [PubMed]  Article 
Target
Name:
Potassium channel subfamily K member 9
Synonyms:
Acid-sensitive potassium channel protein TASK-3 | KCNK9_RAT | Kcnk9 | Potassium channel subfamily K member 9 | TWIK-related acid-sensitive K(+) channel 3 | Task3 | Two pore K(+) channel KT3.2 | Two pore potassium channel KT3.2
Type:
PROTEIN
Mol. Mass.:
44364.88
Organism:
Rattus norvegicus
Description:
ChEMBL_100113
Residue:
396
Sequence:
MKRQNVRTLSLIACTFTYLLVGAAVFDALESDHEMREEEKLKAEEVRLRGKYNISSDDYQQLELVILQSEPHRAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPLTLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTEVSMENMVTVGFFSCMGTLCLGAAAFSQCEDWSFFHAYYYCFITLTTIGFGDFVALQSKGALQRKPFYVAFSFMYILVGLTVIGAFLNLVVLRFLTMNTDEDLLEGEVAQILAGNPRRVVVRVPQSRKRHHPMYFLRKYGRTLCYLCFPGANWGDDDDDDDDAVENVVVTTPVPPAVAAAAAAATPGPSTRNVRATVHSVSCRVEEIPPDVLRNTYFRSPFGAIPPGMHTCGENHRLHIRRKSI
  
Inhibitor
Name:
BDBM50350790
Synonyms:
BUPIVACAINE HYDROCHLORIDE | Bupivacaine | SAMPL3, G1
Type:
Small organic molecule
Emp. Form.:
C18H28N2O
Mol. Mass.:
288.4277
SMILES:
CCCCN1CCCCC1C(=O)Nc1c(C)cccc1C
Structure:
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