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Target
Prostaglandin D2 receptor
Ligand
BDBM50060465
Substrate
n/a
Meas. Tech.
ChEMBL_157792 (CHEMBL768774)
IC50
250±n/a nM
Citation
 Tsuri, T; Honma, T; Hiramatsu, Y; Okada, T; Hashizume, H; Mitsumori, S; Inagaki, M; Arimura, A; Yasui, K; Asanuma, F; Kishino, J; Ohtani, M Bicyclo[2.2.1]heptane and 6,6-dimethylbicyclo[3.1.1]heptane derivatives: orally active, potent, and selective prostaglandin D2 receptor antagonists. J Med Chem 40:3504-7 (1997) [PubMed]  Article 
Target
Name:
Prostaglandin D2 receptor
Synonyms:
Prostaglandin D2 receptor | Prostaglandin D2 | PD2R_HUMAN | PTGDR | Prostanoid DP receptor
Type:
Enzyme
Mol. Mass.:
40288.87
Organism:
Human
Description:
Q13258
Residue:
359
Sequence:
MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPGTWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCTRDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTSEEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
  
Inhibitor
Name:
BDBM50060465
Synonyms:
(Z)-7-[(1S,2R,3R,4R)-3-(4-Phenylethynyl-benzenesulfonylamino)-bicyclo[2.2.1]hept-2-yl]-hept-5-enoic acid | (+) 7-[3-(4-Phenylethynyl-benzenesulfonylamino)-bicyclo[2.2.1]hept-2-yl]-hept-5-enoic acid | CHEMBL82489
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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