Reaction Details Report a problem with these data
Target
TYR_PHOSPHATASE_2 domain-containing protein
Ligand
BDBM50509490
Substrate
n/a
Meas. Tech.
ChEMBL_1838490 (CHEMBL4338623)
Ki
5200±n/a nM
Citation
 Liu, Z; Wang, Q; Li, S; Cui, H; Sun, Z; Chen, D; Lu, Y; Liu, H; Zhang, W Polypropionate Derivatives with  J Nat Prod 82:3440-3449 (2019) [PubMed]  Article 
Target
Name:
TYR_PHOSPHATASE_2 domain-containing protein
Synonyms:
(PROTEIN-TYROSINE-PHOSPHATASE) (PTPase) | MPtpB | PHOSPHOTYROSINE PROTEIN PHOSPHATASE PTPB | Phosphotyrosine protein phosphatase | Phosphotyrosine-protein phosphatase PTPB | Protein Tyrosine Phosphatase PTPB
Type:
Hydrolase
Mol. Mass.:
30152.45
Organism:
Mycobacterium tuberculosis
Description:
n/a
Residue:
276
Sequence:
MAVRELPGAWNFRDVADTATALRPGRLFRSSELSRLDDAGRATLRRLGITDVADLRSSREVARRGPGRVPDGIDVHLLPFPDLADDDADDSAPHETAFKRLLTNDGSNGESGESSQSINDAATRYMTDEYRQFPTRNGAQRALHRVVTLLAAGRPVLTHCFAGKDRTGFVVALVLEAVGLDRDVIVADYLRSNDSVPQLRARISEMIQQRFDTELAPEVVTFTKARLSDGVLGVRAEYLAAARQTIDETYGSLGGYLRDAGISQATVNRMRGVLLG
  
Inhibitor
Name:
BDBM50509490
Synonyms:
CHEMBL4467104
Type:
Small organic molecule
Emp. Form.:
C26H40O6
Mol. Mass.:
448.5922
SMILES:
CC[C@H](COC(C)=O)C[C@H](C)C[C@H](C)C[C@@H](C)\C=C(/C)\C=C(\C=C\C=C\C(O)=O)/C(O)=O |r|
Structure:
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