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Target
Baculoviral IAP repeat-containing protein 2
Ligand
BDBM50450046
Substrate
n/a
Meas. Tech.
ChEMBL_1842326 (CHEMBL4342753)
IC50
12±n/a nM
Citation
 Valenti, D; Hristeva, S; Tzalis, D; Ottmann, C Clinical candidates modulating protein-protein interactions: The fragment-based experience. Eur J Med Chem 167:76-95 (2019) [PubMed]  Article 
Target
Name:
Baculoviral IAP repeat-containing protein 2
Synonyms:
Cellular inhibitor of apoptosis 1 | Baculoviral IAP repeat-containing protein 2 (cIAP1) | Inhibitor of apoptosis protein 2 (cIAP1) | BIRC2_HUMAN | BIRC2 | API1 | MIHB | RNF48
Type:
Protein
Mol. Mass.:
69900.47
Organism:
Human
Description:
Q13490
Residue:
618
Sequence:
MHKTASQRLFPGPSYQNIKSIMEDSTILSDWTNSNKQKMKYDFSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIQKHKQLYPSCSFIQNLVSASLGSTSKNTSPMRNSFAHSLSPTLEHSSLFSGSYSSLSPNPLNSRAVEDISSSRTNPYSYAMSTEEARFLTYHMWPLTFLSPSELARAGFYYIGPGDRVACFACGGKLSNWEPKDDAMSEHRRHFPNCPFLENSLETLRFSISNLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEQLLSTSDTTGEENADPPIIHFGPGESSSEDAVMMNTPVVKSALEMGFNRDLVKQTVQSKILTTGENYKTVNDIVSALLNAEDEKREEEKEKQAEEMASDDLSLIRKNRMALFQQLTCVLPILDNLLKANVINKQEHDIIKQKTQIPLQARELIDTILVKGNAAANIFKNCLKEIDSTLYKNLFVDKNMKYIPTEDVSGLSLEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTVRTFLS
  
Inhibitor
Name:
BDBM50450046
Synonyms:
CHEMBL4173974
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: