Target
G-protein coupled receptor 84
Ligand
BDBM50028336
Substrate
n/a
Meas. Tech.
ChEMBL_1843332
Ki
91±n/a nM
Citation
 Köse, MPillaiyar, TNamasivayam, VDe Filippo, ESylvester, KUlven, Tvon Kügelgen, IMüller, CE An Agonist Radioligand for the Proinflammatory Lipid-Activated G Protein-Coupled Receptor GPR84 Providing Structural Insights. J Med Chem 63:2391-2410 (2020) [PubMed]  Article
Target
Name:
G-protein coupled receptor 84
Synonyms:
EX33 | G-protein coupled receptor 84 | GPR84 | Inflammation-related G-protein coupled receptor EX33
Type:
PROTEIN
Mol. Mass.:
43726.73
Organism:
Homo sapiens (Human)
Description:
ChEMBL_116040
Residue:
396
Sequence:
MWNSSDANFSCYHESVLGYRYVAVSWGVVVAVTGTVGNVLTLLALAIQPKLRTRFNLLIANLTLADLLYCTLLQPFSVDTYLHLHWRTGATFCRVFGLLLFASNSVSILTLCLIALGRYLLIAHPKLFPQVFSAKGIVLALVSTWVVGVASFAPLWPIYILVPVVCTCSFDRIRGRPYTTILMGIYFVLGLSSVGIFYCLIHRQVKRAAQALDQYKLRQASIHSNHVARTDEAMPGRFQELDSRLASGGPSEGISSEPVSAATTQTLEGDSSEVGDQINSKRAKQMAEKSPPEASAKAQPIKGARRAPDSSSEFGKVTRMCFAVFLCFALSYIPFLLLNILDARVQAPRVVHMLAANLTWLNGCINPVLYAAMNRQFRQAYGSILKRGPRSFHRLH
  
Inhibitor
Name:
BDBM50028336
Synonyms:
6-Pentylamino-1H-pyrimidine-2,4-dione | CHEMBL124310
Type:
Small organic molecule
Emp. Form.:
C9H15N3O2
Mol. Mass.:
197.2343
SMILES:
CCCCCNc1cc(=O)[nH]c(=O)[nH]1
Structure:
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