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Target
G-protein coupled receptor 84
Ligand
BDBM50511019
Substrate
n/a
Meas. Tech.
ChEMBL_1843332
Ki
3.1±n/a nM
Citation
 Köse, M; Pillaiyar, T; Namasivayam, V; De Filippo, E; Sylvester, K; Ulven, T; von Kügelgen, I; Müller, CE An Agonist Radioligand for the Proinflammatory Lipid-Activated G Protein-Coupled Receptor GPR84 Providing Structural Insights. J Med Chem 63:2391-2410 (2020) [PubMed]  Article
Target
Name:
G-protein coupled receptor 84
Synonyms:
EX33 | G-protein coupled receptor 84 | GPR84 | Inflammation-related G-protein coupled receptor EX33
Type:
PROTEIN
Mol. Mass.:
43726.73
Organism:
Homo sapiens (Human)
Description:
ChEMBL_116040
Residue:
396
Sequence:
MWNSSDANFSCYHESVLGYRYVAVSWGVVVAVTGTVGNVLTLLALAIQPKLRTRFNLLIANLTLADLLYCTLLQPFSVDTYLHLHWRTGATFCRVFGLLLFASNSVSILTLCLIALGRYLLIAHPKLFPQVFSAKGIVLALVSTWVVGVASFAPLWPIYILVPVVCTCSFDRIRGRPYTTILMGIYFVLGLSSVGIFYCLIHRQVKRAAQALDQYKLRQASIHSNHVARTDEAMPGRFQELDSRLASGGPSEGISSEPVSAATTQTLEGDSSEVGDQINSKRAKQMAEKSPPEASAKAQPIKGARRAPDSSSEFGKVTRMCFAVFLCFALSYIPFLLLNILDARVQAPRVVHMLAANLTWLNGCINPVLYAAMNRQFRQAYGSILKRGPRSFHRLH
  
Inhibitor
Name:
BDBM50511019
Synonyms:
CHEMBL4528577
Type:
Small organic molecule
Emp. Form.:
C12H13N3O3
Mol. Mass.:
247.2499
SMILES:
O=c1cc(NCCOc2ccccc2)[nH]c(=O)[nH]1
Structure:
Search PDB for entries with ligand similarity: