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Target
Capsid protein
Ligand
BDBM50366817
Substrate
n/a
Meas. Tech.
ChEMBL_1852275 (CHEMBL4352899)
IC50
<100±n/a nM
Citation
 Qiu, J; Chen, W; Zhang, Y; Zhou, Q; Chen, J; Yang, L; Gao, J; Gu, X; Tang, D Assessment of quinazolinone derivatives as novel non-nucleoside hepatitis B virus inhibitors. Eur J Med Chem 176:41-49 (2019) [PubMed]  Article 
Target
Name:
Capsid protein
Synonyms:
Core antigen
Type:
PROTEIN
Mol. Mass.:
26278.39
Organism:
Hepatitis B virus
Description:
ChEMBL_450484
Residue:
230
Sequence:
MIFVLGGCRHKLVCSPAPCNFFHLCLIISCSCPTVHASKLCLGWLWGMHIDPYKEFGASVELLSFLPSDFFPSIRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMNLATWVGSNLEDPASRELVVSYVNVNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYRPPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
  
Inhibitor
Name:
BDBM50366817
Synonyms:
Epivir
Type:
Small organic molecule
Emp. Form.:
C8H11N3O3S
Mol. Mass.:
229.256
SMILES:
Nc1ccn([C@@H]2CS[C@H](CO)O2)c(=O)n1 |r|
Structure:
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