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Target
Butyrophilin subfamily 3 member A1
Ligand
BDBM25257
Substrate
n/a
Meas. Tech.
ChEMBL_1866547 (CHEMBL4367522)
EC50
36000±n/a nM
Citation
 Poe, MM; Agabiti, SS; Liu, C; Li, V; Teske, KA; Hsiao, CC; Wiemer, AJ Probing the Ligand-Binding Pocket of BTN3A1. J Med Chem 62:6814-6823 (2019) [PubMed]  Article 
Target
Name:
Butyrophilin subfamily 3 member A1
Synonyms:
BT3A1_HUMAN | BTF5 | BTN3A1 | Butyrophilin subfamily 3 member A1 | CD_antigen=CD277
Type:
PROTEIN
Mol. Mass.:
57685.08
Organism:
Homo sapiens (Human)
Description:
ChEMBL_117363
Residue:
513
Sequence:
MKMASFLAFLLLNFRVCLLLLQLLMPHSAQFSVLGPSGPILAMVGEDADLPCHLFPTMSAETMELKWVSSSLRQVVNVYADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTASDSGKYLCYFQDGDFYEKALVELKVAALGSDLHVDVKGYKDGGIHLECRSTGWYPQPQIQWSNNKGENIPTVEAPVVADGVGLYAVAASVIMRGSSGEGVSCTIRSSLLGLEKTASISIADPFFRSAQRWIAALAGTLPVLLLLLGGAGYFLWQQQEEKKTQFRKKKREQELREMAWSTMKQEQSTRVKLLEELRWRSIQYASRGERHSAYNEWKKALFKPADVILDPKTANPILLVSEDQRSVQRAKEPQDLPDNPERFNWHYCVLGCESFISGRHYWEVEVGDRKEWHIGVCSKNVQRKGWVKMTPENGFWTMGLTDGNKYRTLTEPRTNLKLPKPPKKVGVFLDYETGDISFYNAVDGSHIHTFLDVSFSEALYPVFRILTLEPTALTICPA
  
Inhibitor
Name:
BDBM25257
Synonyms:
({hydroxy[(3-methylbut-3-en-1-yl)oxy]phosphoryl}oxy)phosphonic acid | [14C]IPP | [14C]isopentenyl diphosphate
Type:
radiolabeled substrate
Emp. Form.:
C5H12O7P2
Mol. Mass.:
246.0921
SMILES:
CC(=C)CCOP(O)(=O)OP(O)(O)=O
Structure:
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