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Target
Testis-specific serine/threonine-protein kinase 4
Ligand
BDBM50519662
Substrate
n/a
Meas. Tech.
ChEMBL_1878081 (CHEMBL4379475)
IC50
>10000±n/a nM
Citation
 Zhao, L; Li, Y; Wang, Y; Qiao, Z; Miao, Z; Yang, J; Huang, L; Tian, C; Li, L; Chen, D; Yang, S Discovery of 4 J Med Chem 62:10691-10710 (2019) [PubMed]  Article 
Target
Name:
Testis-specific serine/threonine-protein kinase 4
Synonyms:
2.7.11.1 | Serine/threonine-protein kinase 22E | Synonyms=C14orf20 | TSK-4 | TSSK-4 | Testis-specific kinase 4 | Testis-specific serine/threonine-protein kinase 4 | TSSK4_HUMAN | TSSK4 | C14orf20 | STK22E | TSSK5
Type:
PROTEIN
Mol. Mass.:
37465.51
Organism:
Human
Description:
ChEMBL_118113
Residue:
328
Sequence:
MGKGDVLEAAPTTTAYHSLMDEYGYEVGKAIGHGSYGSVYEAFYTKQKVMVAVKIISKKKASDDYLNKFLPREIQVMKVLRHKYLINFYRAIESTSRVYIILELAQGGDVLEWIQRYGACSEPLAGKWFSQLTLGIAYLHSKSIVHRDLKLENLLLDKWENVKISDFGFAKMVPSNQPVGCSPSYRQVNCFSHLSQTYCGSFAYACPEILRGLPYNPFLSDTWSMGVILYTLVVAHLPFDDTNLKKLLRETQKEVTFPANHTISQECKNLILQMLRQATKRATILDIIKDSWVLKFQPEQPTHEIRLLEAMCQLHNTTKQHQSLQITT
  
Inhibitor
Name:
BDBM50519662
Synonyms:
CHEMBL4438748
Type:
Small organic molecule
Emp. Form.:
C26H23N3O5
Mol. Mass.:
457.49
SMILES:
CN(C)c1ccc(cc1)C(=O)Nc1cccc(NC(=O)COc2ccc3c(c2)occc3=O)c1
Structure:
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