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Target
Thromboxane A2 receptor
Ligand
BDBM50075083
Substrate
n/a
Meas. Tech.
ChEBML_221825
IC50
77600.0±n/a nM
Citation
 Shinozaki, K; Sato, H; Iwakuma, T; Sato, R; Kurimoto, T; Yoshida, K Synthesis and thromboxane A2 antagonistic activity activity of indane derivatives. Bioorg Med Chem Lett 9:401-6 (1999) [PubMed]  Article  BDB Entry
Target
Name:
Thromboxane A2 receptor
Synonyms:
Prostanoid TP receptor | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta
Type:
Enyzme
Mol. Mass.:
37445.28
Organism:
Homo sapiens (Human)
Description:
P21731
Residue:
343
Sequence:
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
  
Inhibitor
Name:
BDBM50075083
Synonyms:
CHEMBL340073 | Sodium; {2-[(pentane-1-sulfonylamino)-methyl]-indan-5-yl}-acetate
Type:
Small organic molecule
Emp. Form.:
C17H24NO4S
Mol. Mass.:
338.442
SMILES:
CCCCCS(=O)(=O)NCC1Cc2ccc(CC([O-])=O)cc2C1
Structure:
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