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Target
Vasopressin V1b receptor
Ligand
BDBM50075720
Substrate
n/a
Meas. Tech.
ChEMBL_214688 (CHEMBL817651)
Ki
5.9±n/a nM
Citation
 Durroux, T; Peter, M; Turcatti, G; Chollet, A; Balestre, MN; Barberis, C; Seyer, R Fluorescent pseudo-peptide linear vasopressin antagonists: design, synthesis, and applications. J Med Chem 42:1312-9 (1999) [PubMed]  Article 
Target
Name:
Vasopressin V1b receptor
Synonyms:
Vasopressin V3 receptor | AVPR V3 | AVPR V1b | Antidiuretic hormone receptor 1b | V1bR | VASOPRESSIN V1B | Vasopressin V3 | AVPR3 | VPR3 | V1BR_HUMAN | AVPR1B | Vasopressin V1b receptor | Vasopressin V1b receptor (V1b)
Type:
Enzyme
Mol. Mass.:
46985.01
Organism:
Human
Description:
P47901
Residue:
424
Sequence:
MDSGPLWDANPTPRGTLSAPNATTPWLGRDEELAKVEIGVLATVLVLATGGNLAVLLTLGQLGRKRSRMHLFVLHLALTDLAVALFQVLPQLLWDITYRFQGPDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLQQPGQSTYLLIAAPWLLAAIFSLPQVFIFSLREVIQGSGVLDCWADFGFPWGPRAYLTWTTLAIFVLPVTMLTACYSLICHEICKNLKVKTQAWRVGGGGWRTWDRPSPSTLAATTRGLPSRVSSINTISRAKIRTVKMTFVIVLAYIACWAPFFSVQMWSVWDKNAPDEDSTNVAFTISMLLGNLNSCCNPWIYMGFNSHLLPRPLRHLACCGGPQPRMRRRLSDGSLSSRHTTLLTRSSCPATLSLSLSLTLSGRPRPEESPRDLELADGEGTAETIIF
  
Inhibitor
Name:
BDBM50075720
Synonyms:
(HO-LVA23)2-{2-[3-(4-Hydroxy-phenyl)-2-(methyl-4-Hydroxy-phenylacetyl-amino)-propionylamino]-3-phenyl-propionylamino}-pentanedioic acid 5-amide 1-[(2-carbamoyl-1-{1-[2-(1-carbamoyl-4-guanidino-butylcarbamoyl)-pyrrolidine-1-carbonyl]-4-guanidino-butylcarbamoyl}-ethyl)-amide] | CHEMBL269012
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
CN([C@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(N)=O)C(=O)Cc1ccc(O)cc1
Structure:
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