Reaction Details Report a problem with these data
Target
Vasopressin V1a receptor
Ligand
BDBM50075726
Substrate
n/a
Meas. Tech.
ChEMBL_214419 (CHEMBL820283)
Ki
>500±n/a nM
Citation
 Durroux, T; Peter, M; Turcatti, G; Chollet, A; Balestre, MN; Barberis, C; Seyer, R Fluorescent pseudo-peptide linear vasopressin antagonists: design, synthesis, and applications. J Med Chem 42:1312-9 (1999) [PubMed]  Article 
Target
Name:
Vasopressin V1a receptor
Synonyms:
Vasopressin receptor | Vasopressin V1a receptor | AVPR V1a | Antidiuretic hormone receptor 1a | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | V1AR_HUMAN | AVPR1A | AVPR1
Type:
Receptor
Mol. Mass.:
46820.18
Organism:
Human
Description:
P37288
Residue:
418
Sequence:
MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
  
Inhibitor
Name:
BDBM50075726
Synonyms:
tetraethylrhodamyl-DTyr(Me)-Phe-Gln-Asn-Arg-Pro-Arg-Tyr-NH2 | CHEMBL409756
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
CCN(CC)C1=CC2Oc3cc(ccc3[C+](C2C=C1)c1ccccc1C(=O)N(C)[C@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)N(CC)CC |c:19,t:5|
Structure:
Search PDB for entries with ligand similarity: