Target
Glucagon-like peptide 1 receptor
Ligand
BDBM50241203
Substrate
n/a
Meas. Tech.
ChEMBL_1898208 (CHEMBL4400243)
EC50
0.006±n/a nM
Citation
 Li, CCai, XDai, YLiu, CBi, XZhou, JLi, QSun, LHuang, WHou, ZQian, H Novel lipid side chain modified exenatide analogs emerged prolonged glucoregulatory activity and potential body weight management properties. Bioorg Med Chem 27:0 (2019) [PubMed]  Article 
Target
Name:
Glucagon-like peptide 1 receptor
Synonyms:
GLP-1 receptor | GLP-1-R | GLP-1R | GLP1R | GLP1R_HUMAN | Glucagon-like peptide 1 receptor | Glucagon-like peptide 1 receptor (GLP-1)
Type:
Enzyme
Mol. Mass.:
53035.78
Organism:
Homo sapiens (Human)
Description:
P43220
Residue:
463
Sequence:
MAGAPGPLRLALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERWRLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTATCQASCS
  
Inhibitor
Name:
BDBM50241203
Synonyms:
CHEMBL414357 | HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGSPPPS-NH2 | exenatide | exendin-4
Type:
Small organic molecule
Emp. Form.:
C184H282N50O60S
Mol. Mass.:
4186.572
SMILES:
n/a
Structure:
Search PDB for entries with ligand similarity: