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Target
85/88 kDa calcium-independent phospholipase A2
Ligand
BDBM50526357
Substrate
n/a
Meas. Tech.
ChEMBL_1899861 (CHEMBL4401976)
IC50
3500±n/a nM
Citation
 Dedaki, C; Kokotou, MG; Mouchlis, VD; Limnios, D; Lei, X; Mu, CT; Ramanadham, S; Magrioti, V; Dennis, EA; Kokotos, G β-Lactones: A Novel Class of Ca J Med Chem 62:2916-2927 (2019) [PubMed]  Article 
Target
Name:
85/88 kDa calcium-independent phospholipase A2
Synonyms:
PLPL9_HUMAN | PLA2G6 | PLPLA9 | Calcium-independent phospholipase A2
Type:
PROTEIN
Mol. Mass.:
89913.62
Organism:
Human
Description:
ChEMBL_156048
Residue:
806
Sequence:
MQFFGRLVNTFSGVTNLFSNPFRVKEVAVADYTSSDRVREEGQLILFQNTPNRTWDCVLVNPRNSQSGFRLFQLELEADALVNFHQYSSQLLPFYESSPQVLHTEVLQHLTDLIRNHPSWSVAHLAVELGIRECFHHSRIISCANCAENEEGCTPLHLACRKGDGEILVELVQYCHTQMDVTDYKGETVFHYAVQGDNSQVLQLLGRNAVAGLNQVNNQGLTPLHLACQLGKQEMVRVLLLCNARCNIMGPNGYPIHSAMKFSQKGCAEMIISMDSSQIHSKDPRYGASPLHWAKNAEMARMLLKRGCNVNSTSSAGNTALHVAVMRNRFDCAIVLLTHGANADARGEHGNTPLHLAMSKDNVEMIKALIVFGAEVDTPNDFGETPTFLASKIGRLVTRKAILTLLRTVGAEYCFPPIHGVPAEQGSAAPHHPFSLERAQPPPISLNNLELQDLMHISRARKPAFILGSMRDEKRTHDHLLCLDGGGVKGLIIIQLLIAIEKASGVATKDLFDWVAGTSTGGILALAILHSKSMAYMRGMYFRMKDEVFRGSRPYESGPLEEFLKREFGEHTKMTDVRKPKVMLTGTLSDRQPAELHLFRNYDAPETVREPRFNQNVNLRPPAQPSDQLVWRAARSSGAAPTYFRPNGRFLDGGLLANNPTLDAMTEIHEYNQDLIRKGQANKVKKLSIVVSLGTGRSPQVPVTCVDVFRPSNPWELAKTVFGAKELGKMVVDCCTDPDGRAVDRARAWCEMVGIQYFRLNPQLGTDIMLDEVSDTVLVNALWETEVYIYEHREEFQKLIQLLLSP
  
Inhibitor
Name:
BDBM50526357
Synonyms:
CHEMBL4439384
Type:
Small organic molecule
Emp. Form.:
C16H22O2
Mol. Mass.:
246.35
SMILES:
CCC[C@@H]1OC(=O)[C@@H]1CCCCc1ccccc1 |r|
Structure:
Search PDB for entries with ligand similarity: