Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM50018958
Substrate
n/a
Meas. Tech.
ChEMBL_1903849 (CHEMBL4406071)
EC50
0.420000±n/a nM
Citation
 Tan, L; Zhou, Q; Yan, W; Sun, J; Kozikowski, AP; Zhao, S; Huang, XP; Cheng, J Design and Synthesis of Bitopic 2-Phenylcyclopropylmethylamine (PCPMA) Derivatives as Selective Dopamine D3 Receptor Ligands. J Med Chem 63:4579-4602 (2020) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DRD3_HUMAN | DRD3 | Dopamine D3 receptor (D3R) | Dopamine D3 receptor (D3) | Dopamine D3 receptor | DOPAMINE D3 | Dopamine receptor | Dopamine receptor D3 | Dopamine receptor (D3)
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Human
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50018958
Synonyms:
CHEBI:75401 | QUINPIROLE
Type:
Small organic molecule
Emp. Form.:
C13H21N3
Mol. Mass.:
219.17
SMILES:
[H][C@]12CCCN(CCC)[C@]1([H])Cc1c[nH]nc1C2
Structure:
Search PDB for entries with ligand similarity: