Reaction Details Report a problem with these data
Target
Kappa-type opioid receptor
Ligand
BDBM50090103
Substrate
n/a
Meas. Tech.
ChEMBL_145814 (CHEMBL753526)
Ki
0.354±n/a nM
Citation
 Stevens, WC; Jones, RM; Subramanian, G; Metzger, TG; Ferguson, DM; Portoghese, PS Potent and selective indolomorphinan antagonists of the kappa-opioid receptor. J Med Chem 43:2759-69 (2000) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
KOR-1 | Kappa Opioid Receptor | OPIATE Kappa | OPRK_RAT | Opioid receptor | Oprk1 | Ror-d
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42692.90
Organism:
Rattus norvegicus (rat)
Description:
P34975
Residue:
380
Sequence:
MESPIQIFRGEPGPTCAPSACLLPNSSSWFPNWAESDSNGSVGSEDQQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSAVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLASSVGISAIVLGGTKVREDVDVIECSLQFPDDEYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITKLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAVLSSYYFCIALGYTNSSLNPVLYAFLDENFKRCFRDFCFPIKMRMERQSTNRVRNTVQDPASMRDVGGMNKPV
  
Inhibitor
Name:
BDBM50090103
Synonyms:
5'-(Trimethylammonium)methyl-17-cyclopropylmethyl-6,7-didehydro-4,5alpha-epoxy-3,14-dihydroxyindolo[2',3':6,7]morphinan Iodide | CHEMBL92665
Type:
Small organic molecule
Emp. Form.:
C30H36N3O3
Mol. Mass.:
486.6246
SMILES:
C[N+](C)(C)Cc1ccc2[nH]c3[C@@H]4Oc5c6c(CC7N(CC8CC8)CC[C@@]46[C@@]7(O)Cc3c2c1)ccc5O |TLB:13:14:26:18.24.23,32:15:26:18.24.23|
Structure:
Search PDB for entries with ligand similarity: