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Target
Eukaryotic translation initiation factor 4E
Ligand
BDBM50543774
Substrate
n/a
Meas. Tech.
ChEMBL_1989849 (CHEMBL4623584)
IC50
1400±n/a nM
Citation
 Golojuch, S; Kopcial, M; Strzelecka, D; Kasprzyk, R; Baran, N; Sikorski, PJ; Kowalska, J; Jemielity, J Exploring tryptamine conjugates as pronucleotides of phosphate-modified 7-methylguanine nucleotides targeting cap-dependent translation. Bioorg Med Chem 28:0 (2020) [PubMed]  Article 
Target
Name:
Eukaryotic translation initiation factor 4E
Synonyms:
IF4E_RABIT | EIF4E
Type:
PROTEIN
Mol. Mass.:
25047.40
Organism:
Rabbit
Description:
ChEMBL_1511842
Residue:
217
Sequence:
MATVEPETTPTPNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
  
Inhibitor
Name:
BDBM50543774
Synonyms:
CHEMBL4640855
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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