Reaction Details Report a problem with these data
Target
Serine protease 1
Ligand
BDBM50101133
Substrate
n/a
Meas. Tech.
ChEBML_212339
IC50
39000±n/a nM
Citation
 Aoyama, Y; Uenaka, M; Konoike, T; Hayasaki-Kajiwara, Y; Naya, N; Nakajima, M Inhibition of serine proteases: activity of 1,3-diazetidine-2,4-diones. Bioorg Med Chem Lett 11:1691-4 (2001) [PubMed]  Article 
Target
Name:
Serine protease 1
Synonyms:
Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I
Type:
Enzyme
Mol. Mass.:
25790.52
Organism:
Bos taurus (bovine)
Description:
P00760
Residue:
246
Sequence:
MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN
  
Inhibitor
Name:
BDBM50101133
Synonyms:
1,3-Diethyl-[1,3]diazetidine-2,4-dione | CHEMBL298276
Type:
Small organic molecule
Emp. Form.:
C6H10N2O2
Mol. Mass.:
142.1558
SMILES:
CCN1C(=O)N(CC)C1=O
Structure:
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