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Target
D(1A) dopamine receptor
Ligand
BDBM50004822
Substrate
n/a
Meas. Tech.
ChEMBL_1991502 (CHEMBL4625237)
Ki
1.000000±n/a nM
Citation
 Giri, R; Namballa, HK; Sarker, A; Alberts, I; Harding, WW Synthesis and dopamine receptor pharmacological evaluations on ring C ortho halogenated 1-phenylbenzazepines. Bioorg Med Chem Lett 30:0 (2020) [PubMed]  Article 
Target
Name:
D(1A) dopamine receptor
Synonyms:
DA D1 receptor | DOPAMINE D1 | Dopamine D1 receptor | Dopamine D1 receptor (D1R) | Dopamine D1A | DRD1_HUMAN | DRD1
Type:
Enzyme
Mol. Mass.:
49303.43
Organism:
Human
Description:
P21728
Residue:
446
Sequence:
MRTLNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
  
Inhibitor
Name:
BDBM50004822
Synonyms:
CHEMBL24077 | SKF 38393 (+) | SK-383933 | R(+)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol | SKF 38393 | SK-38393 | 1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol | 1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF38393) | (R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol | CHEMBL1467585 | SK&F-383933 | 7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(R(+)SKF38393) | (R)-7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
Oc1cc2CCNC[C@H](c3ccccc3)c2cc1O
Structure:
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