Reaction Details Report a problem with these data
Target
Prostaglandin E2 receptor EP2 subtype
Ligand
BDBM50101824
Substrate
n/a
Meas. Tech.
ChEMBL_158306 (CHEMBL763191)
EC50
33±n/a nM
Citation
 Tani, K; Naganawa, A; Ishida, A; Egashira, H; Sagawa, K; Harada, H; Ogawa, M; Maruyama, T; Ohuchida, S; Nakai, H; Kondo, K; Toda, M Design and synthesis of a highly selective EP2-receptor agonist. Bioorg Med Chem Lett 11:2025-8 (2001) [PubMed]  Article 
Target
Name:
Prostaglandin E2 receptor EP2 subtype
Synonyms:
Prostaglandin E2 | Prostaglandin E2 receptor EP2 subtype | PGE receptor, EP2 subtype | PE2R2_MOUSE | Ptger2 | Ptgerep2 | Prostanoid EP2 receptor
Type:
G-protein coupled receptor
Mol. Mass.:
40495.26
Organism:
Mouse
Description:
n/a
Residue:
362
Sequence:
MDNFLNDSKLMEDCKSRQWLLSGESPAISSVMFSAGVLGNLIALALLARRWRGDTGCSAGSRTSISLFHVLVTELVLTDLLGTCLISPVVLASYSRNQTLVALAPESHACTYFAFTMTFFSLATMLMLFAMALERYLSIGYPYFYRRHLSRRGGLAVLPVIYGASLLFCSLPLLNYGEYVQYCPGTWCFIRHGRTAYLQLYATMLLLLIVAVLACNISVILNLIRMHRRSRRSRCGLSGSSLRGPGSRRRGERTSMAEETDHLILLAIMTITFAICSLPFTIFAYMDETSSLKEKWDLRALRFLSVNSIIDPWVFAILRPPVLRLMRSVLCCRTSLRTQEAQQTSCSTQSSASKQTDLCGQL
  
Inhibitor
Name:
BDBM50101824
Synonyms:
Butaprost (Methyl Ester) | BUTAPROST | CHEMBL432522 | 7-{(1R,3R)-3-Hydroxy-2-[(E)-(S)-4-hydroxy-4-(1-propyl-cyclobutyl)-but-1-enyl]-5-oxo-cyclopentyl}-heptanoic acid methyl ester
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: