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Target
Prostaglandin E2 receptor EP4 subtype
Ligand
BDBM50101842
Substrate
n/a
Meas. Tech.
ChEMBL_158447 (CHEMBL763251)
EC50
4.3±n/a nM
Citation
 Maruyama, T; Asada, M; Shiraishi, T; Ishida, A; Egashira, H; Yoshida, H; Maruyama, T; Ohuchida, S; Nakai, H; Kondo, K; Toda, M Design and synthesis of a highly selective EP4-receptor agonist. Part 1: 3,7-dithiaPG derivatives with high selectivity. Bioorg Med Chem Lett 11:2029-31 (2001) [PubMed]  Article 
Target
Name:
Prostaglandin E2 receptor EP4 subtype
Synonyms:
PGE receptor, EP4 subtype | PE2R4_MOUSE | Ptger4 | Ptgerep4 | Prostanoid EP4 receptor
Type:
G-protein coupled receptor
Mol. Mass.:
56175.66
Organism:
Mouse
Description:
n/a
Residue:
513
Sequence:
MAEVGGTIPRSNRELQRCVLLTTTIMSIPGVNASFSSTPERLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGDQALCDYSTFILLFFGLSGLSIICAMSIERYLAINHAYFYSHYVDKRLAGLTLFAIYASNVLFCALPNMGLGRSERQYPGTWCFIDWTTNVTAYAAFSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAAAVASVACRGHAGASPALQRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFINQLYQPNVVKDISRNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSGRDSSAQHCSESRRTSSAMSGHSRSFLARELKEISSTSQTLLYLPDLTESSLGGRNLLPGSHGMGLTQADTTSLRTLRISETSDSSQGQDSESVLLVDEVSGSHREEPASKGNSLQVTFPSETLKLSEKCI
  
Inhibitor
Name:
BDBM50101842
Synonyms:
{3-[(S)-(R)-3-Hydroxy-2-((1S,2R)-3-hydroxy-oct-1-enyl)-5-oxo-cyclopentylsulfanyl]-propylsulfanyl}-acetic acid | CHEMBL64217
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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