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Target
C-X-C chemokine receptor type 2
Ligand
BDBM50102217
Substrate
n/a
Meas. Tech.
ChEBML_39662
IC50
32±n/a nM
Citation
 Cutshall, NS; Ursino, R; Kucera, KA; Latham, J; Ihle, NC Nicotinamide N-oxides as CXCR2 antagonists. Bioorg Med Chem Lett 11:1951-4 (2001) [PubMed]  Article 
Target
Name:
C-X-C chemokine receptor type 2
Synonyms:
C-X-C chemokine receptor type 2 (CXCR-2) | C-X-C chemokine receptor type 2 (CXCR2) | CD_antigen=CD182 | CDw128b | CXCR-2 | CXCR2 | CXCR2_HUMAN | Chemokine receptor type 2 (CXCR2) | GRO/MGSA receptor | High affinity interleukin-8 receptor B | IL-8 receptor type 2 | IL-8R B | IL8RB | Interleukin-8 receptor B
Type:
Protein
Mol. Mass.:
40767.88
Organism:
Homo sapiens (Human)
Description:
P25025
Residue:
360
Sequence:
MEDFNMESDSFEDFWKGEDLSNYSYSSTLPPFLLDAAPCEPESLEINKYFVVIIYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNGWIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYLVKFICLSIWGLSLLLALPVLLFRRTVYSSNVSPACYEDMGNNTANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCERRNHIDRALDATEILGILHSCLNPLIYAFIGQKFRHGLLKILAIHGLISKDSLPKDSRPSFVGSSSGHTSTTL
  
Inhibitor
Name:
BDBM50102217
Synonyms:
3-[5-(4-Fluoro-phenylcarbamoyl)-1-oxy-pyridine-2-sulfonyl]-benzoic acid | CHEMBL57680
Type:
Small organic molecule
Emp. Form.:
C19H13FN2O6S
Mol. Mass.:
416.38
SMILES:
OC(=O)c1cccc(c1)S(=O)(=O)c1ccc(c[n+]1[O-])C(=O)Nc1ccc(F)cc1
Structure:
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