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Target
Prostaglandin D2 receptor
Ligand
BDBM50035622
Substrate
n/a
Meas. Tech.
ChEMBL_158168 (CHEMBL766131)
IC50
4500±n/a nM
Citation
 Soper, DL; Milbank, JB; Mieling, GE; Dirr, MJ; Kende, AS; Cooper, R; Jee, WS; Yao, W; Chen, JL; Bodman, M; Lundy, MW; De, B; Stella, ME; Ebetino, FH; Wang, Y; deLong, MA; Wos, JA Synthesis and biological evaluation of prostaglandin-F alkylphosphinic acid derivatives as bone anabolic agents for the treatment of osteoporosis. J Med Chem 44:4157-69 (2001) [PubMed]  Article 
Target
Name:
Prostaglandin D2 receptor
Synonyms:
PD2R_HUMAN | PTGDR | Prostaglandin D2 | Prostaglandin D2 receptor | Prostanoid DP receptor
Type:
Enzyme
Mol. Mass.:
40288.87
Organism:
Homo sapiens (Human)
Description:
Q13258
Residue:
359
Sequence:
MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPGTWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCTRDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTSEEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
  
Inhibitor
Name:
BDBM50035622
Synonyms:
(5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dien-1-oic acid | CHEMBL815 | DINOPROST | PGF2alpha | l-PGF2-alpha | l-Prostaglandin F2-alpha | prostaglandin F2alpha
Type:
Small organic molecule
Emp. Form.:
C20H34O5
Mol. Mass.:
354.481
SMILES:
CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O |r|
Structure:
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