Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM82053
Substrate
n/a
Meas. Tech.
ChEMBL_2028569 (CHEMBL4682727)
Ki
14000±n/a nM
Citation
 Abdelrahman, A; Yerande, SG; Namasivayam, V; Klapschinski, TA; Alnouri, MW; El-Tayeb, A; Müller, CE Substituted 4-phenylthiazoles: Development of potent and selective A Eur J Med Chem 186:0 (2020) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM82053
Synonyms:
8-(2-Furyl)theophylline | US9138393, Theophylline | US9144538, Theophylline
Type:
n/a
Emp. Form.:
C7H8N4O2
Mol. Mass.:
180.164
SMILES:
Cn1c2[nH]cnc2c(=O)n(C)c1=O
Structure:
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